Sodium thiopental: better known as Sodium Pentothal (a trademark of Abbott Laboratories), thiopental, thiopentonesodium, or Trapanal (also a trademark), is a rapid-onset short-acting barbiturate general anaesthetic.
Thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia. intravenous injection the drug rapidly reaches the brain and causes unconsciousness within 30–45 seconds. At one minute, the drug attains a peak concentration of about 60% of the total dose in the brain. Thereafter, the drug distributes to the rest of the body and in about 5–10 minutes the concentration is low enough in the brain such that consciousness returnsA normal dose of thiopental (usually 4–6 mg/kg) given to a pregnant woman for operative delivery (caesarian section) rapidly makes her unconscious, but the baby in her uterus remains conscious. However, larger or repeated doses can depress the baby.
2.5% (1gm in 40ml)
40 ml vial
4.2/5
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