Laxatives

Milk of magnesia:

Magnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)₂. As a suspension in water, it is often called milk of magnesia because of its milk-like appearance. The solid mineral form of magnesium hydroxide is known as brucite.

Uses:

Suspensions of magnesium hydroxide in water (milk of magnesia) are used as an antacid to neutralize stomach acid, and a laxative. The diarrhea caused by magnesium hydroxide carries away much of the body's supply of potassium, and failure to take extra potassium may lead to muscle cramps. Magnesium hydroxide is also used as an antiperspirant armpit deodorant Milk of magnesia is useful against canker sores (aphthous ulcer) when used topically.                                        It is primarily used to alleviate constipation, but also to relieve indigestion and heartburn.  When taken orally as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. It is also used as an antacid, though more modern formulations combine the antimotility effects of equal concentrations of aluminum hydroxide to avoid unwanted laxative effects.

Medicinal liquid paraffin is a very highly refined mineral white oil used in cosmetics and for medical purposes.

Usage: Liquid paraffin - as Liquid Paraffin Oral Emulsion BP - is considered to have a limited usefulness as an occasional laxative, but is unsuitable for regular use as it can seep from the anus and cause irritation; it can interfere with the absorption of fat-soluble vitamins; it can be absorbed into the intestinal wall and may cause foreign-body granulamatous reactions; and if it enters the lungs it can cause lipoid pneumonia. Liquid paraffin also forms an ingredient of the osmotic laxative "Magnesium & Liquid Paraffin"

Sucralfate is an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers. Sucralfate is also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers. Unlike the other classes of medications used for treatment of peptic ulcers, sucralfate is a sucrose sulfate-aluminium complex that binds to the hydrochloric acid in the stomach and acts like an acid buffer with cytoprotective properties. Sucralfate was approved by the U.S. Food and Drug Administration (FDA) in 1981.


Clinical uses: The only FDA-approved indication for sucralfate is for the treatment of active duodenal ulcers not related to NSAID usage because the mechanism behind these ulcers is secondary to acid oversecretion. It is not technically approved for gastric ulcers because the main mechanism is not due to acid oversecretion but rather from diminished protection. The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prophylaxis.

Bisacodyl  is a stimulant laxative drug. It is typically prescribed for relief of constipation and for the management of neurogenic bowel dysfunction as well as part of bowel preparation before medical examinations. Bisacodyl is a diphenylmethane derivative and was first used as a laxative in 1953 due to its similarity to phenolphthalein.

5 mg

1000 tabs